Aproximaciones lingüísticas a la hipótesis de la modularidad de la mente

In this article we argue that linguistic evidence, particularly coming from language pathologies, point out that Fodor’s Modularity of Mind Hypothesis is too strong. In its place we defend a weaker version of it, meaning that the language faculty is not conditioned by any specific sensorial modality, as signed languages show, and where modular systems can interact among them

Sobre el Estatuto Lingüístico de las lenguas de señas

El objetivo de este artículo es reivindicar que las lenguas de señas o signos son sistemas lingüísticos naturales y no códigos artificiales de comunicación y que, por tanto, deben ser estudiadas como tales desde las disciplinas científicas. Con este objetivo, presentamos evidencias Neurolingüísticas y Psicolingüísticas que contradicen este prejuicio lingüístico arraigado en nuestra sociedad e incluso en ámbitos académicos universitarios

Innovación, docencia e investigación como cambio y transformación en el ámbito de la publicación universitaria: International Journal of Educational Research and Innovation

-Artículo revisado por pare

Diseño de una férula de muñeca impresa en 3D con soporte para un exoesqueleto de los dedos de la mano.

El presente Trabajo de Fin de Grado pretende llegar a marcar un antes y un después en la evolución y desarrollo de férulas ortopédicas, un material sanitario que a nivel económico no se encuentra disponible para un amplio marco de la población y cuyos materiales dificultan su uso. Con este proyecto se pretende crear una férula dinámica de muñeca con un amplio número de funciones para pacientes con problemas de movilidad, cognitivos, posibles fisuras y, especialmente, en pacientes con rotura de tendones flexores de los dedos de la mano. El motivo del enfoque centrado en esta última premisa es el elevado porcentaje de operaciones de tendones causados por cortes en el trabajo manual y es que, a pesar de esto, hoy en día todavía no hay disponible un sistema de ayuda y rehabilitación postoperatorio específico. Además, esta férula está al alcance de toda la población gracias a su bajo coste, aporta gran calidad de comodidad gracias a su elevada ligereza conseguida por medio del uso de impresión aditiva y tiene un diseño muy sencillo que permite ser usado sin limitación alguna de conocimientos específicos. Gracias a su diseño modular se ha conseguido también un producto sostenible, cuyas piezas pueden ser recicladas por separado y sustituidas de manera individual sin necesidad de desperdiciar la ortesis completamente en caso de fisuras o roturas. Cabe destacar que su posibilidad de personalización mejorará la calidad del proceso de rehabilitación reflejándose, por consiguiente, en una mejora de la calidad de vida del pacient

Estrategias para la formación e innovación universitarias en tiempos de pandemia

In this article, I set out to demonstrate the need for a student-centred model, which would enable students, through the proper effective use of ICT, to develop critical awareness, creativity, and knowledge. However, this process must be mediated by a teacher who is competent in the use of ICT and knows how to get the most out of them, so that teaching becomes more than merely a "container" of content. This paper presents a brief chronological overview of the events of the pandemic and its most immediate consequences of moving from face-to-face teaching to online delivery in such a short space of time. Finally, it will review the actions carried out by the Universidad Pablo de Olavide, in Seville, in the field of training and innovation.En este artículo he tratado de evidenciar la necesidad de que se opte de manera definitiva por un modelo centrado en el alumno de manera que sean ellos los que a través de las TIC y el buen uso de éstas se conviertan en personas con sentido crítico, con creatividad y conocimiento. Pero en este proceso se hace fundamental la mediación del docente que debe conocer no ya las TIC sino cómo se le puede sacar el máximo partido para que la docencia no sea un mero "contenedor" de contenidos. Se expondrá una breve reseña cronológica de los acontecimientos de la pandemia y las consecuencias más inmediatas al pasar de una enseñanza de carácter presencial a otra online en tan poco tiempo. Y finamente se reseñarán las actuaciones en el ámbito de la formación e innovación llevada a cabo dese la Universidad Pablo de Olavide de Sevilla (UPO).Universidad Pablo de Olavid

Cavity Backed Slot Antenna Fed by a Stripline with SIW Structure and Vertical Coaxial Transition for Microwave Solid State Heating Applications

[EN] This paper presents a new approach to feed multimode cavities used as microwave applicators for industrial and domestic microwave ovens using solid-state sources operating in the 2.45 GHz ISM (Industrial, Scientific and Medical) band (commonly used for industrial microwave applications). The feeding structure consists of a slot on the top side of the applicator cavity. The slot is fed by a shielded asymmetric stripline with a Substrate Integrated Waveguide structure (to preserve the stripline Transversal Electro-Magnetic (TEM) operation within the shield) and is N-connectorized. A first design of the antenna was obtained using state-of-the-art antenna theory assuming free-space radiation. Then, it was refined using a commercial simulation tool based on the Finite Element Method in the frequency domain to achieve VSWR values lower than 1.5 in the source bandwidth (from 2.42 to 2.48 GHz) when the antenna radiates into the applicator cavity. The design parameters of all the components making up this feeding structure are discussed throughout the paper. A prototype was built and measured in the laboratory. The experimental results are presented at the end of the paper along with the simulated ones, showing a very good agreement.This research was funded by Generalitat Valenciana, grant number FDGENT/2018/008.Santón, P.; De Los Reyes, R.; Balbastre Tejedor, JV. (2022). Cavity Backed Slot Antenna Fed by a Stripline with SIW Structure and Vertical Coaxial Transition for Microwave Solid State Heating Applications. Electronics. 11(3):1-10. https://doi.org/10.3390/electronics1103032711011

An effective procedure to design the layout of standard and enhanced mode-S multilateration systems for airport surveillance

In this paper, an effective procedure to emplace standard and enhanced mode-S multilateration stations for airport surveillance is studied and developed. This procedure is based on meta-heuristic optimization techniques, such as genetic algorithm (GA), and is intended to obtain useful parameters for an optimal system configuration that provides acceptable performance levels. Furthermore, the procedure developed here is able to evaluate and improve previous system designs, as well as possible system enhancements. Additionally, the design strategies to be used along with the procedure proposed here are fully described. Parameters such as the number of stations, the system geometry, the kind of measurements to be used, and the system accuracy are obtained taking into account the basic requirements such as the Line of Sight, the probability of detection, and the accuracy levels. © Cambridge University Press and the European Microwave Association, 2012

Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes

Ezrin, radixin, and moesin (ERM) regulate cortical morphogenesis and cell adhesion by connecting membrane adhesion receptors to the actin-based cytoskeleton. We have studied the interaction of moesin and ezrin with the vascular cell adhesion molecule (VCAM)-1 during leukocyte adhesion and transendothelial migration (TEM). VCAM-1 interacted directly with moesin and ezrin in vitro, and all of these molecules colocalized at the apical surface of endothelium. Dynamic assessment of this interaction in living cells showed that both VCAM-1 and moesin were involved in lymphoblast adhesion and spreading on the endothelium, whereas only moesin participated in TEM, following the same distribution pattern as ICAM-1. During leukocyte adhesion in static or under flow conditions, VCAM-1, ICAM-1, and activated moesin and ezrin clustered in an endothelial actin-rich docking structure that anchored and partially embraced the leukocyte containing other cytoskeletal components such as α-actinin, vinculin, and VASP. Phosphoinositides and the Rho/p160 ROCK pathway, which participate in the activation of ERM proteins, were involved in the generation and maintenance of the anchoring structure. These results provide the first characterization of an endothelial docking structure that plays a key role in the firm adhesion of leukocytes to the endothelium during inflammation

Solar-Simulated Ultraviolet Radiation Induces Abnormal Maturation and Defective Chemotaxis of Dendritic Cells

Exposure to ultraviolet (UV) light induces immunosuppression. Different evidences indicate that this phenomenon is mainly a consequence of the effect of UV light on skin dendritic cells (DC). To investigate the cellular and molecular basis of this type of immunosuppression, we assessed in vitro the effect of solar-simulated UV radiation on the phenotypic and functional characteristics of human monocyte-derived DC and Langerhans-like DC. UV radiation induced a decreased expression of molecules involved in antigen capture as DC-SIGN and the mannose receptor. This effect was accompanied by a diminished endocytic capacity, an enhanced expression of molecules involved in antigen presentation such as major histocompatibility complex-II and CD86, and a significant increase in their capability to stimulate T cells. Furthermore, irradiated DC failed to acquire a full mature phenotype upon treatment with lipopolysaccharide. On the other hand, solar-simulated radiation induced the secretion of tumor necrosis factor-αand interleukin (IL)-10 by DC, but no IL-12. Interestingly, solar-simulated UV radiation also caused an altered migratory phenotype, with an increased expression of CXCR4, and a lack of induction of CCR7, thus correlating with a high chemotactic response to stromal cell-derived factor 1(SDF-1) (CXCL12), but not to secondary lymphoid tissue chemokine (SLC) (CCL21). These data indicate that solar-simulated UV radiation induces a defective maturation and an anomalous migratory phenotype of DC